Manager / Senior Scientist Mass Spectrometry

Main Tasks:

• Lead and develop the mass spectrometry laboratory ensuring scientific and technical excellence and operational efficiency to advance FK biosimilars development.
• Develop, establish and execute mass spectrometry protocols relevant to biosimilars’ characterization and similarity assessment (intact mass, subunits analysis, PTMs, sequencing, peptide mapping, disulfide bridge mapping, etc.).
• Support analytical strategy adapted to development phases (early and late) as per regulatory guidelines.
• Provide mass spectrometry and molecular characterization expertise to stakeholders and project management teams.
• Manage instruments’ operations, calibration, maintenance, setting up of new methods and equipment, and method improvements.
• Troubleshoot issues with instruments and methods.
• Oversee method development, qualification, data acquisition, data analysis, and interpretation.
• Apply data integrity principles of R&D QMS for compliant data generation and reporting.
• Interpret and report results internally and externally, review and approve operating procedures and analytical reports.
• Plan experiments, assign resources, and deliver results according to project timelines.
• Provide project support, communicate progress, align with other labs and escalate resource prioritization issues.
• Manage personnel performance and development to ensure achievement of goals, motivation, and productivity.

Qualification profile:

Education and languages:

• University degree in relevant area: PhD + minimum 4 years’ experience or MSc + minimum 8 years’ experience in Biotech/Pharma industry.
• Fluent in English (spoken and written); French is a plus.

Professional skills and experience:

• Strong experience in mass spectrometry mAb and recombinant protein characterization and method development.
• Good understanding of monoclonal antibodies, critical quality attributes and structure-function relationships.
• Advanced knowledge and experience in peptide mapping, intact mass analysis and LC-MS workflows for biotherapeutics characterization.
• Fluency in proteomics approaches (identification and quantification).
• Proven people and stakeholder management skills; team player with analytical and critical thinking.
• Experience evaluating and implementing new technologies.
• Experience on Thermo Q-Orbitrap FTMS platform is a plus.

Personal Skills and Competencies:

• Detail-oriented, highly organized and accurate.
• Ability to independently plan, prioritize, and manage multiple activities and projects.
• Scientific data evaluation skills at different stages of development.
• Initiative and proactive mindset.
• Team worker able to maintain motivating working atmosphere.